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Dr. Magryta: Is marijuana safe for use?

Is marijuana safe for use? The American sentiment seems to be shifting that way, especially out in the wild west. When it comes to drugs that affect the brain, we have to be very careful to conclude this on a population level.

College students have to leave school every year secondary to psychological breaks that are induced by drug use including marijuana. I witnessed this first hand as I went to a very small school and things of this nature were hard to hide.

For me, the biggest concern with recreational drug use has always been the long term effects on the young mind. In December’s Scientific American, there is an article entitled Marijuana and the Teen Brain. It is a good read and I encourage you to read it. As author, Claudia Wallis, points out, parents have been warning teens away from drugs for centuries only for teens to hide in the woods and smoke before school with a smile. And yes, I do remember the high school students, “burnouts”, who did this daily in the woods behind my school.

Studies have shown that marijuana users have worsened attention, memory and learning. We know that some users can become delusional and even have psychotic breaks. What we do not know is who will and who won’t. Some college students appear to be able to smoke often and remain fully functional as they are able to graduate and hold gainful employment. Whether they suffered weakened attention and memory would only be known with a pre and post assessment.

In states that have legalized marijuana use, there has been a 0.5% increase in HS dropout and a 2% decrease in college enrollment. That is a lot of children when you look at the number of states that have legalized marijuana and the volume of students overall.

Evidence seems to point to safety for use in adults where the brain is not growing and changing. In a meta analysis from 2012, the authors noted that after 25 days off of the drug, the users had no difference in cognitive function versus the non users.

Not so much for teen brains!

“For one thing, recent studies show that cannabinoids manufactured by our own nerve cells play a crucial role in wiring the brain, both prenatally and during adolescence. Throughout life they regulate appetite, sleep, emotion, memory and movement which makes sense when you consider the effects of marijuana. There are “huge changes” in the concentration of these endocannabinoids during the teenage years, according to neurologist Yasmin Hurd of the Icahn School of Medicine at Mount Sinai, which is why she and others who study this system worry about the impact of casually dosing it with weed.”

The body actually makes similar substances naturally all the time. There are receptors in the brain for this family of chemicals making it a concern for us if teenagers are saturating these receptors beyond what would normally happen in nature.

Some other disturbing findings are noted in the brain scans of users versus non users. Users have smaller amygdala and hippocampal volumes which means weakened emotional regulation and memory function. They also have reinforced this concern in animal studies that have shown that rats exposed to high dose marijuana during puberty suffered cognitive decline that was not present during adulthood.

What is clear to me when thinking of the brain and development is that certain people are predisposed to poorer outcomes when exposed to an abnormal negative external stimulus. Think of concussions here: some people receive the same type of hit and one suffers a significant concussion where another does not. We know from epigenetic studies that mammals have different responses to external stressors and I assume that this is the same with drugs of recreation like marijuana. This seems to be the case by my observational experience.

Many young adolescents use drugs like marijuana to numb a psychological pain or current stressor. Is that persistent experiential negativity at the root of cognitive decline as well? I hypothesize that this is also correct. Couple stress, epigenetics and drug effects together and I think that we can safely say that using these drugs during puberty is not in one’s best interest.

Mitigating the stressors of adolescence is where we should focus our efforts.

I highly recommend that all teenagers read a few books:

–Extreme Ownership by Jocko Willink (my favorite)

–Inch and Miles by John Wooden

–Anything You Want by Derek Sivers

–Jonathon Livingston Seagull by Richard Bach

Meditation is a great place to start for stress reduction: look at the Mindfulness for Teens, Headspace or Calm websites.

Daily prayer and gratitude journals are also highly beneficial.

Consider taking your teen to a counselor for life coaching and stress reduction. Visit The Adult Chair for lessons on parenting a teen.

Consider mission trips and local charity work to keep everything in perspective.

As always, stay in their lives and keep parenting them as long as you can,

Dr. M

Dr. Chris Magryta is a physician at Salisbury Pediatric Associates. Contact him at newsletter@salisburypediatrics.com 

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